GMP · GxP · PIC/S · SAHPRA Inspection

Inspection-ready. From day one.

End-to-end GMP site setup, SAHPRA inspection preparation, QA/QC system design, equipment validation, and GxP training — for pharmaceutical manufacturers, cannabis operations, and API producers across Africa.

GMP
Certified adviser
PIC/S
Standard aligned
QP
Services available
3
Site types covered

GMP services

Every stage of GMP compliance.

Mishonga provides the complete GMP compliance service stack — from facility design and SOP development through inspection preparation, validation, QP certification, and ongoing compliance management.

01
GMP site design & setup
Facility design review, material flow mapping, HVAC and cleanroom specification, equipment selection, and SOP development — from concept through SAHPRA pre-approval inspection.
Site designCleanroomHVACSOPsPre-approval
02
SAHPRA inspection preparation
Mock inspections, gap analyses against PIC/S guidelines, corrective action plans, and inspection day readiness — for routine surveillance, pre-approval, and for-cause inspections.
Mock inspectionPIC/SGap analysisCAPASurveillance
03
QA/QC system development
Quality Management System design — SOPs, batch records, deviation and change control, OOS procedures, and Annual Product Quality Reviews aligned to SAHPRA and international standards.
QMSChange controlOOSAPQRSOPs
04
Validation & qualification
Equipment qualification (IQ/OQ/PQ), process validation, cleaning validation, computer system validation, and analytical method validation — fully documented and SAHPRA-ready.
IQ/OQ/PQProcess val.CSVMethod val.Cleaning val.
05
Qualified person (QP) services
QP certification and batch release services for pharmaceutical and cannabis manufacturing — standing QP or project-based for product launches and site registrations.
QPBatch releaseCertificationStanding QP
06
GxP training programmes
Custom GMP, GDP, GLP, GCP, and GACP training — designed for your team, your regulatory environment, your products. On-site, virtual, or hybrid with assessment and certification.
GMP trainingGDPGACPGLPCustom

Licences & permits — manufacturing to retail

Every licence your operation needs to run.

Mishonga manages the full manufacturing, wholesale, and retail licence application lifecycle — from pharmaceutical GMP through environmental authorisations and petroleum business licensing.

Pharmaceutical
SAHPRA manufacturing licence (GMP)
Full GMP manufacturing licence applications for sterile, non-sterile, solid dose, liquid, and API sites — dossier preparation and inspection readiness.
Pharmaceutical
Wholesale distributor licence (GDP)
SAHPRA wholesale distributor licence — GDP SOP package, temperature mapping, facility compliance, and annual renewal management.
Pharmaceutical
Retail pharmacy licence (SAPC)
SAPC community, hospital, and specialist pharmacy licence applications — premises, RP appointment, and compliance documentation.
Cannabis
SAHPRA Section 22A manufacturing
Cannabis manufacturing licence applications across all three SAHPRA tiers — Tier 1 hemp through Schedule 7 pharmaceutical THC.
Environmental
Environmental authorisations (EIA/WML)
EIA and Waste Management Licence applications for manufacturing and processing facilities — DFFE and provincial environmental authority submissions.
Petroleum
Petroleum manufacturing licence (DMRE)
DMRE petroleum manufacturing licence — facility compliance, SANS standards, environmental requirements, and NERSA notification.
Petroleum
Petroleum wholesale licence
Petroleum wholesale licence — bulk liquid fuel storage compliance, SANS 10131, NERSA licensing, and environmental permit coordination.
Petroleum
Petroleum retail licence (service station)
DMRE petroleum retail site licence — site compliance, zoning, EIA, NERSA registration, and oil company agreement alignment.

Frequently asked

Common questions from clients.

How long does a SAHPRA GMP manufacturing licence take?
Typically 6–18 months from application to licence issue, depending on site type and whether a pre-approval inspection is required. Mishonga's gap analysis and mock inspection process significantly reduces inspection failure risk and re-inspection delays.
Can Mishonga help with petroleum retail licensing from scratch?
Yes. Mishonga manages the complete petroleum retail licence application — site compliance assessment, EIA application, DMRE submission, NERSA registration, and oil company site agreement alignment — as a single coordinated engagement.
Do you provide ongoing compliance management after licence issue?
Yes. Ongoing compliance management is available on retainer — covering renewals, annual submissions, variation applications, SAHPRA surveillance inspection readiness, and regulatory change monitoring.
What is a QP and when do I need one?
A Qualified Person (QP) is the individual legally responsible for certifying that each batch of medicinal product has been manufactured and tested in accordance with the relevant marketing authorisation. SAHPRA requires a designated QP for all licensed pharmaceutical manufacturing sites. Mishonga provides standing QP or locum QP services.

Get your site inspection-ready.

Tell us your site type, current stage, and target timeline — we'll respond with a scoped proposal within 48 hours.

Request a proposal → Email Denver directly